Opening series at Fenway.
Opening Day – Fenway Park 4-10-81
Red Sox 4, White Sox 0
WP: Dennis Eckersley (1-0)
LP: Britt Burns (0-1)
HR’s: Red Sox – Carl Yaztrezemski (1), Dave Stapleton (1)
Eckersley with a 5 hitter
4-12-81
White Sox 6, Red Sox 5
WP: Kevin Hickey (1-0)
LP: Bill Campbell (0-1)
Save: LaMarr Hoyt (1)
HR’s: White Sox – Tony Bernazard (1), Chet Lemon (1)
Teams split this opening weekend series.